{"product_id":"ieej-mbe11135","title":"末梢交感神経活動電位を用いた糖尿病性神経障害の評価","description":"\u003cp\u003e\u003cstrong\u003eカテゴリ: \u003c\/strong\u003e研究会(論文単位)\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e論文No: \u003c\/strong\u003eMBE11135\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eグループ名: \u003c\/strong\u003e【C】電子・情報・システム部門 医用・生体工学研究会\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e発行日: \u003c\/strong\u003e2011\/09\/21\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eタイトル(英語): \u003c\/strong\u003eEvaluation of diabetic neuropathy using peripheral sympathetic-nerve action potentials\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e著者名: \u003c\/strong\u003e佐藤 政文(山形大学),新澤 剛(山形大学),狩俣 徹(山形大学),内藤 学(山形大学),楠 正隆(愛知医科大学),中村 孝夫(山形大学)\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e著者名(英語): \u003c\/strong\u003eSato Masafumi(Yamagata University),Shinzawa Go(Yamagata University),Karimata Toru(Yamagata University),Naito Manabu(Yamagata University),Kusunoki Masataka(Aichi Medical University),Nakamura Takao(Yamagata University)\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e要約(日本語): \u003c\/strong\u003eTo examine the possibility of evaluation of diabetic neuropathy with sympathetic nerve activity (SNA) derived microneurographically, 4 groups (Normal, STZ-3wks, STZ+ARI and STZ-1wk) of rats were used. Streptozotocin (STZ) was administered ip to each rat at 8 weeks of age in STZ-3wks and STZ+ARI groups, and at 10 weeks for STZ-1wk. Aldose reductase inhibitor (ARI) was orally given daily to STZ+ARI group after the STZ administration. At 11 weeks, sympathetic nerve signal was derived from the sciatic nerve of each rat using the microneurographic technique. After steady-state sympathetic activity was recorded, glucose was administered iv (IVGA), and the action potential (AP) rate was evaluated. The steady-state AP-rate in STZ-3wks group was lower than that in the other 3 groups. The SNA responding to IVGA gradually increased in Normal and STZ-1wk groups, whereas it showed little change in STZ-3wks and STZ-ARI groups. The results suggest that the feasibility of AP-rate in evaluating neuropathy.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e原稿種別: \u003c\/strong\u003e日本語\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePDFファイルサイズ: \u003c\/strong\u003e627 Kバイト\u003c\/p\u003e","brand":"IEEJ-PDF","offers":[{"title":"PDFダウンロード（一般価格330円\/会員価格220円） \/ A4 \/ 3","offer_id":46380715147503,"sku":"IEEJ-MBE11135-PDF","price":330.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/9512\/2159\/files\/IEEJ-PDF_66af958c-1a87-4eff-90fa-823f7b9db82b.png?v=1744204019","url":"https:\/\/ieej.bookpark.ne.jp\/products\/ieej-mbe11135","provider":"電気学会 電子図書館","version":"1.0","type":"link"}