{"product_id":"ieej-zt133108","title":"微小管を用いた高感度タウタンパク質検出法","description":"\u003cp\u003e\u003cstrong\u003eカテゴリ: \u003c\/strong\u003e全国大会\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e論文No: \u003c\/strong\u003e3-108\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eグループ名: \u003c\/strong\u003e【全国大会】平成25年電気学会全国大会論文集\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e発行日: \u003c\/strong\u003e2013\/03\/05\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eタイトル(英語): \u003c\/strong\u003eDevelopment of a highly sensitive microtubule based tau detection method\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e著者名: \u003c\/strong\u003eオラゾフイスラム (東京大学),タルハンチャータイ (東京大学),横川 隆司(京都大学),カースタンスタニスラフ (NeuroInDx,Inc.),藤田 博之(東京大学)\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e著者名(英語): \u003c\/strong\u003eYslam Orazov(The University of Tokyo),Cagatay Tarhan(The University of Tokyo),Ryuji Yokokawa(Kyoto university),Stanislav Karsten(NeuroInDx,Inc.),Hiroyuki Fujita(The University of Tokyo)\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eキーワード: \u003c\/strong\u003e微小管|キネシン|タウタンパク質|神経伝達\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e要約(日本語): \u003c\/strong\u003eMicrotubule (MT)-based intraneuronal transport is often altered in several neurological diseases. To understand complex molecular processes underlying MT-based neuronal transport, e.g. stabilization of MT by its associated proteins, a reliable and sensitive in vitro assay is required. Such assay would permit analysis of various conditions and components affecting MT-based transport, facilitating identification of drugs modulating disease course, and ultimately resulting in the development of new theraupetic approaches. This paper focuses on improving the protein-MT interaction assay based on reconstructed kinesin\/microtubule system. Different MT immobilization processes were compared on tau protein detection. The system using MTs suspended between microstructures provided higher statistical significance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e原稿種別: \u003c\/strong\u003e日本語\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePDFファイルサイズ: \u003c\/strong\u003e520 Kバイト\u003c\/p\u003e","brand":"IEEJ-PDF","offers":[{"title":"PDFダウンロード（一般価格440円\/会員価格220円） \/ A4 \/ 1","offer_id":46399809552623,"sku":"IEEJ-ZT133108-PDF","price":440.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0718\/9512\/2159\/files\/IEEJ-PDF_bcd2535a-4219-433c-a4c3-769c4b1f7355.png?v=1744909544","url":"https:\/\/ieej.bookpark.ne.jp\/products\/ieej-zt133108","provider":"電気学会 電子図書館","version":"1.0","type":"link"}