Liquid Layer Thickness Control and Adjustment in Gas-phase Odor Biosensor

カテゴリ: 研究会(論文単位)

論文No: CHS23003

グループ名: 【E】センサ・マイクロマシン部門 ケミカルセンサ研究会

発行日: 2023/02/28

タイトル(英語): Liquid Layer Thickness Control and Adjustment in Gas-phase Odor Biosensor

著者名: Deng Hongchao(東京工業大学),光野 秀文(東京大学),神崎 亮平(東京大学),中本 高道(東京工業大学)

著者名(英語): Hongchao Deng(Tokyo Insititute of Technology),Hidefumi Mitsuno(The University of Tokyo),Ryohei Kanzaki(The University of Tokyo),Takamichi Nakamoto(Tokyo Insititute of Technology)

キーワード: Ｇａｓ－ｐｈａｓｅ|Ｏｄｏｒ　ｂｉｏｓｅｎｓｏｒ|Ｆｅｅｄｂａｃｋ　ｃｏｎｔｒｏｌ|Ｌｉｑｕｉｄ　ｔｈｉｃｋｎｅｓｓ|Gas-phase|Odor biosensor|Feedback control|Liquid thickness

要約(日本語): The odor biosensors based on cell expressing OR were first introduced in the liquid phase. To extend the application scenarios of these biosensors from liquid phase into gas phase, a thin liquid film covering the sensing cells was preferred because it ensures the aqueous environment for preserving the cell viability and also allows the hydrophobic odorant molecules to penetrate it. In this paper, we illustrated a feedback control method for maintaining the thin liquid layer. The actuator could be electroosmotic (EO) pump or syringe pump. In addition, the fine adjustment of liquid film thickness is also introduced. With these techniques, long biosensor lifetime and favorable biosensor responses could be obtained.

要約(英語): The odor biosensors based on cell expressing OR were first introduced in the liquid phase. To extend the application scenarios of these biosensors from liquid phase into gas phase, a thin liquid film covering the sensing cells was preferred because it ensures the aqueous environment for preserving the cell viability and also allows the hydrophobic odorant molecules to penetrate it. In this paper, we illustrated a feedback control method for maintaining the thin liquid layer. The actuator could be electroosmotic (EO) pump or syringe pump. In addition, the fine adjustment of liquid film thickness is also introduced. With these techniques, long biosensor lifetime and favorable biosensor responses could be obtained.

本誌: 2023年3月3日ケミカルセンサ研究会

本誌掲載ページ: 13-17 p

原稿種別: 英語

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