Development of skin insertion type biological substance measuring system

カテゴリ: 研究会(論文単位)

論文No: MSS23019,CHS23015,BMS23007

グループ名: 【E】センサ・マイクロマシン部門 マイクロマシン・センサシステム/【E】センサ・マイクロマシン部門 ケミカルセンサ/【E】センサ・マイクロマシン部門 バイオ・マイクロシステム合同研究会

発行日: 2023/03/25

タイトル(英語): Development of skin insertion type biological substance measuring system

著者名: Tsuruoka Noriko(Tohoku University)

著者名(英語): Noriko Tsuruoka(Tohoku University)

キーワード: Microperfusion|Non-planar microfabrication|Biological substance monitoring|Enzyme electrode|Lactate measurement|Bubble removal|Microperfusion|Non-planar microfabrication|Biological substance monitoring|Enzyme electrode|Lactate measurement|Bubble removal

要約(日本語): Concentrations of biological substances are useful as an indicator of our health. In order to monitor biological substances, the device which does microperfusion in subepidermal tissue was developed. Our device is aiming for skin patch type sensor system which consists of pump, skin inserting needle and biological substance sensor. The microperfusion needle has enough rigidity for inserting through the skin by using acupuncture needle. The flow channel and perforated membrane were made by polyimide on the surface of a thin steel acupuncture needle using our developed non-planar microfabrication process. For measuring lactate, one of the target biological substance, concentration of perfusate continuously, enzyme electrode sensor with two-layer bubble removal flow channel was fabricated.

要約(英語): Concentrations of biological substances are useful as an indicator of our health. In order to monitor biological substances, the device which does microperfusion in subepidermal tissue was developed. Our device is aiming for skin patch type sensor system which consists of pump, skin inserting needle and biological substance sensor. The microperfusion needle has enough rigidity for inserting through the skin by using acupuncture needle. The flow channel and perforated membrane were made by polyimide on the surface of a thin steel acupuncture needle using our developed non-planar microfabrication process. For measuring lactate, one of the target biological substance, concentration of perfusate continuously, enzyme electrode sensor with two-layer bubble removal flow channel was fabricated.

本誌: 2023年3月28日-2023年3月29日マイクロマシン・センサシステム/ケミカルセンサ/バイオ・マイクロシステム合同研究会

本誌掲載ページ: 25-29 p

原稿種別: 英語

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