単球様細胞マクロファージにおける大気圧酸素プラズマ活性種の影響

カテゴリ: 部門大会

論文No: 1-B-p2-2

グループ名: 【A】令和3年電気学会基礎・材料・共通部門大会

発行日: 2021/09/01

著者名: 永田 香澄（九州大学）, 林 信哉（九州大学）

キーワード: atmospheric pressure plasma|oxygen plasma|phagocytosis|macrophage|ozone|immunotherapy

要約(日本語): Immunotherapy is a new cancer treatment method by using immune cells. Atmospheric pressure oxygen plasma is used for generation of ozone and endeavor to active macrophages those are a kind of immune cells. The effect of ozone on phagocytosis of macrophages is investigated by adjusting the irradiation time and ozone concentration. The phagocytosis increased 1.4 times higher than control after long-term irradiation with ozone concentration of 25 ppm. In comparison, the short-term irradiation with 100 ppm increased by only 1.1 times. Therefore, it was clarified that long-term low-concentration ozone irradiation is more effective in enhancing the phagocytosis of macrophages avoiding the damage to the cells.

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