【Invited】Developments of Molecularly Imprinted Polymer-Based Protein Sensing Platforms

カテゴリ: 部門大会

論文No: 2-C-p1-5

グループ名: 【A】令和６年電気学会基礎・材料・共通部門大会

発行日: 2024/08/26

タイトル(英語): 【Invited】Developments of Molecularly Imprinted Polymer-Based Protein Sensing Platforms

著者名: Park Jinyoung(Kyungpook National University)

キーワード: Protein imprinting|melittin|imprinting factor|interleukin-1β

要約(日本語): For the accurate detection of macromolecular proteins, biomimetically designed sensing platforms with high sensitivity and selectivity need to be developed including easy manufacturing, ease of mass production, and breadth of functional material selection. Molecular imprinting (MI) produces the artificial receptors with high-affinity binding sites in a polymer matrix through crosslinking in the presence of a target material (template). However, the imprinting of large biomolecules face limitations owing to their large size, chemical and structural complexity, and environmental instability. Thus, in this work we introduce two efficient approaches to protein detection platforms based on molecularly imprinted polymers (MIPs).

要約(英語): For the accurate detection of macromolecular proteins, biomimetically designed sensing platforms with high sensitivity and selectivity need to be developed including easy manufacturing, ease of mass production, and breadth of functional material selection. Molecular imprinting (MI) produces the artificial receptors with high-affinity binding sites in a polymer matrix through crosslinking in the presence of a target material (template). However, the imprinting of large biomolecules face limitations owing to their large size, chemical and structural complexity, and environmental instability. Thus, in this work we introduce two efficient approaches to protein detection platforms based on molecularly imprinted polymers (MIPs).

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