Development of ultrasound-controllable DNA nanotubes

カテゴリ: 部門大会

論文No: SS1-7

グループ名: 【C】2023年電気学会電子・情報・システム部門大会

発行日: 2023/08/23

タイトル(英語): Development of ultrasound-controllable DNA nanotubes

著者名: Tagai Yukine（東京工業大学）,Kanno Shoichiro（東京工業大学）,Peng Zugui（東京工業大学）,Shimba Kenta（東京大学）,Miyamoto Yoshitaka（成育医療研究センター/東京工業大学）,Yagi Tohru（東京工業大学）

著者名(英語): Yukine Tagai (Tokyo Institute of Technology),Shoichiro Kanno (Tokyo Institute of Technology),Zugui Peng (Tokyo Institute of Technology),Kenta Shimba (The University of Tokyo),Yoshitaka Miyamoto (National Research Institute for Child Health and Development/Tokyo Institute of Technology),Tohru Yagi (Tokyo Institute of Technology)

キーワード: DNA nanotechnology|nanotubes|ultrasound|lipid bilayer|vesicles

要約(日本語): Nanotubes are nanostructures that can control the transport of materials and signals through membranes. DNA nanotubes, a type of nanotube, are composed of DNA and can be designed with predicted structures based on the specificity of base pairs, enabling nanotubes with complex structures and functions. DNA bundle nanotubes are formed by only a few strands to control the opening and closing of nanotubes by external triggers such as DNA strand, heat, and light. However, one that can be triggered by mechanical stimuli has not yet been developed. Therefore, we aim to develop DNA bundle nanotubes that can be controlled using ultrasound, a mechanical stimulus. We prepare DNA bundle nanotubes as the basis of this research and evaluate their membrane permeation performance.