A Study of DNA Nanotubes with Lids That Can Be Controlled to Open and Close by Ultrasound Irradiation.

カテゴリ: 部門大会

論文No: SS1-7

グループ名: 【C】2024年電気学会電子・情報・システム部門大会

発行日: 2024/08/28

タイトル(英語): A Study of DNA Nanotubes with Lids That Can Be Controlled to Open and Close by Ultrasound Irradiation.

著者名: 吉崎 翔大（東京工業大学）,菅野 翔一朗（東京工業大学）,彭 祖癸（東京工業大学）,榛葉 健太（東京大学）,宮本 義孝（国立研究開発法人国立成育医療研究センター・研究所）,八木 透（東京工業大学）

著者名(英語): Shota Yoshizaki (Tokyo Institute of Technology),Shoichiro Kanno (Tokyo Institute of Technology),Peng Zugui (Tokyo Institute of Technology),Kenta Shimba (The University of Tokyo),Yoshitaka Miyamoto (National Research institute for Child Health and Development),Tohru Yagi (Tokyo Institute of Technology)

キーワード: DNAナノチューブ|ナノチューブ|DNAナノテクノロジー|超音波|脂質小胞|DNA nanotubes|nanotubes|DNA nanotechnology|ultrasound|small unilamellar vesicle

要約(日本語): Nanotubes are structures that control the transport of substances in and out of artificial cell membranes. Research on nanotubes is important in the development of biosensing and drug release devices. DNA nanotubes are nanotubes made of DNA, which allows them to have various functions. In previous studies, DNA nanotubes whose lid opening and closing can be controlled by various kinds of stimuli have been proposed. Unlike the previous DNA nanotubes, we aim to develop the one with lids that can be controlled to open and close by ultrasound irradiation (US-DNA nanotubes). A US-DNA nanotube consist of a tubular base (DNA nanotube) and two lids (Lock1, Lock2). In this study, we confirmed the synthesis of Lock1 and Lock2 and the binding of locks to DNA nanotube by electrophoresis.