Axon guidance and differentiation via microchannels

カテゴリ: 部門大会

論文No: PS2-5

グループ名: 【C】2019年電気学会電子・情報・システム部門大会プログラム

発行日: 2019/08/28

タイトル(英語): Axon guidance and differentiation via microchannels

著者名: Rix Graham(東京工業大学),Sungha Jeon(東京工業大学),Miyata Hiromu(東京工業大学),Shimba Kenta(東京大学),Miyamoto Yoshitaka(東京工業大学),Yagi Tohru(東京工業大学)

著者名(英語): Graham Rix|Jeon Sungha|Hiromu Miyata|Kenta Shimba|Yoshitaka Miyamoto|Tohru Yagi

キーワード: Axon Guidance|Neuron|Neural Regeneration|Neural Differentiation

要約(日本語): Microchannel devices are a promising tool for the development of sensory-capable neural prosthetics. Current limitations in the field involve low resolution of stimulation for sensory neurons, as well as poor distinction between the type of sensation to be elicited. The goal of this research will be to evaluate the feasibility of guiding axon growth through microchannels while differentiating source neurons between proprioceptive and nociceptive types. To do this, we plan to develop a device with sub-15um channels connecting neurons to separated reservoirs containing specific nerve growth factors for each type.

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