MICROFLUIDIC BASED TRANSMISSION SURFACE PLASMON RESONANCE FOR BIOSENSOR APPLICATIONS

カテゴリ: 研究会(論文単位)

論文No: DEI16025

グループ名: 【A】基礎・材料・共通部門 誘電・絶縁材料研究会

発行日: 2016/01/12

タイトル(英語): MICROFLUIDIC BASED TRANSMISSION SURFACE PLASMON RESONANCE FOR BIOSENSOR APPLICATIONS

著者名: Lertvachirapaiboon Chutiparn(Niigata University),Baba Akira(Niigata University),Ekgasit Sanong(Chulalongkorn University),Shinbo Kazunari(Niigata University),Kato Keizo(Niigata University),Kaneko Futao(Niigata University)

著者名(英語): Chutiparn Lertvachirapaiboon(Niigata University),Akira Baba(Niigata University),Sanong Ekgasit(Chulalongkorn University),Kazunari Shinbo(Niigata University),Keizo Kato(Niigata University),Futao Kaneko(Niigata University)

キーワード: Transmission surface plasmon resonance|microfluidic|silver nanoparticles|biosensors|Transmission surface plasmon resonance|microfluidic|silver nanoparticles|biosensors

要約(日本語): Transmission surface plasmon resonance (TSPR) has become a topic of interest because a large electric field induces strong and narrow spectra in the visible to near-infrared region. TSPR was first observed on gold nanohole arrays, later, this phenomenon was also observed on gold grating patterns. In this work, we further enhanced the TSPR intensity by depositing silver nanoparticles (AgNPs) on a gold grating substrate. The TSPR spectrum of the gold grating substrate with AgNPs showed a strong and narrow SPR peak located between 650 and 800 nm. The maximum SPR excitation was observed at an incident angle of 35 degree. We controlled the distance between the gold grating surface and the AgNPs by using Layer-by-Layer (LbL) ultrathin films of poly(allylamine hydrochloride) (PAH) and poly(sodium 4-styrenesulfonate) (PSS) to study the distant dependence of coupling effect between the AgNPs and the gold grating substrate. The maximum coupling of the surface plasmons was observed at an intermediate layer thickness of 10 bilayers. This hybrid material was integrated into the microfluidic system. A polydimethylsiloxane elastomer was used to fabricate the microfluidic channel before attaching on developed substrate. The sensitivity of microfluidic based TSPR of gold grating substrate with AgNPs was better than bare gold grating substrate for 4.7 times. This system was employed for bio/chemical sensor applications and nanomaterials characterization.

要約(英語): Transmission surface plasmon resonance (TSPR) has become a topic of interest because a large electric field induces strong and narrow spectra in the visible to near-infrared region. TSPR was first observed on gold nanohole arrays, later, this phenomenon was also observed on gold grating patterns. In this work, we further enhanced the TSPR intensity by depositing silver nanoparticles (AgNPs) on a gold grating substrate. The TSPR spectrum of the gold grating substrate with AgNPs showed a strong and narrow SPR peak located between 650 and 800 nm. The maximum SPR excitation was observed at an incident angle of 35 degree. We controlled the distance between the gold grating surface and the AgNPs by using Layer-by-Layer (LbL) ultrathin films of poly(allylamine hydrochloride) (PAH) and poly(sodium 4-styrenesulfonate) (PSS) to study the distant dependence of coupling effect between the AgNPs and the gold grating substrate. The maximum coupling of the surface plasmons was observed at an intermediate layer thickness of 10 bilayers. This hybrid material was integrated into the microfluidic system. A polydimethylsiloxane elastomer was used to fabricate the microfluidic channel before attaching on developed substrate. The sensitivity of microfluidic based TSPR of gold grating substrate with AgNPs was better than bare gold grating substrate for 4.7 times. This system was employed for bio/chemical sensor applications and nanomaterials characterization.

原稿種別: 英語

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