マウス一次視覚野電気刺激による高次視覚野への信号伝播様式の解析

カテゴリ: 研究会(論文単位)

論文No: MBE11129

グループ名: 【C】電子・情報・システム部門 医用・生体工学研究会

発行日: 2011/09/21

タイトル(英語): Spatio-temporal properties of signal propagation to the extrastriatal areas studied by electrical stimulation to the mouse primary visual cortex

著者名: 岡崎 祐香(大阪保健医療大学),フェヘルヴァリ タマシュ(大阪大学),石川 直裕(大阪大学),山口 俊平(大阪大学),八木 哲也(大阪大学)

著者名(英語): Okazaki Yuka(Osaka Health Science University),Fehervari Tamas(Osaka University),Ishikawa Naohiro(Osaka University),Yamaguchi Shunpei(Osaka University),Yagi Tetsuya(Osaka University)

要約(日本語): We conducted in vivo voltage-sensitive dye imaging on the mouse occipital cortex toinvestigate the signal transmission properties from the striate to extrastriate cortical areas. Biphasic intracortical stimulations (intensity: 5-80 μA, duration: 200 μs/phase, frequency: 10-200 Hz) were delivered to the mouse primary visual cortex (V1). The cortical activities evoked by the stimuli were recorded with high speed CMOS image sensor (100×100 pixels, 1 ms/frame). The activitiy evoked by the V1 stimulation spread within V1 and to extrastriate areas including latero-medial area (LM), which is homologous of human secondary visual cortex (V2). These activities were enlarged and magnified by the stimulation with higher frequency, subsequently the area shrank during the stimulation. These results are useful for desining of the implant electrodes and parameters of stimulus..

原稿種別: 日本語

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