In vivo evaluation of cortical hemodynamics and depolarization in rat brain with a digital red-green-blue camera

カテゴリ: 研究会(論文単位)

論文No: OQD17003

グループ名: 【C】電子・情報・システム部門 光・量子デバイス研究会

発行日: 2017/03/06

タイトル(英語): In vivo evaluation of cortical hemodynamics and depolarization in rat brain with a digital red-green-blue camera

著者名: Nishidate Izumi(Tokyo University of Agriculture and Technology),Mustari Afrina(Tokyo University of Agriculture and Technology),Kawauchi Satoko(National Defense Medical College Research Institute),Sato Shunichi(National Defense Medical College Research Institute),Sato Manabu(Yamagata University),Kokubo Yasuaki(Yamagata University Faculty of Medicine)

著者名(英語): Izumi Nishidate(Tokyo University of Agriculture and Technology),Afrina Mustari(Tokyo University of Agriculture and Technology),Satoko Kawauchi(National Defense Medical College Research Institute),Shunichi Sato(National Defense Medical College Research Institute),Manabu Sato(Yamagata University),Yasuaki Kokubo(Yamagata University Faculty of Medicine)

キーワード: RGB camera|cortical spreading depolarization|hemodynamics|scattering parameter|Monte Carlo simulation|multiple regression analysis|RGB camera|cortical spreading depolarization|hemodynamics|scattering parameter|Monte Carlo simulation|multiple regression analysis

要約(日本語): We propose a rapid imaging method to monitor the spatial distribution of total hemoglobin concentration, the regional oxygen saturation, and the scattering power b as the scattering parameters in cerebral cortex using a digital red-green-blue camera. In the method, the RGB-values are converted into the tristimulus values in CIEXYZ color space. Monte Carlo simulation is used to specify a relation among the XYZ-values and the concentrations of oxygenated hemoglobin, deoxygenated hemoglobin, and the scattering parameter. In vivo experiments with exposed brain of rats during cortical spreading depression indicate potential of the method to evaluate the pathophysiological conditions in brain tissue.

要約(英語): We propose a rapid imaging method to monitor the spatial distribution of total hemoglobin concentration, the regional oxygen saturation, and the scattering power b as the scattering parameters in cerebral cortex using a digital red-green-blue camera. In the method, the RGB-values are converted into the tristimulus values in CIEXYZ color space. Monte Carlo simulation is used to specify a relation among the XYZ-values and the concentrations of oxygenated hemoglobin, deoxygenated hemoglobin, and the scattering parameter. In vivo experiments with exposed brain of rats during cortical spreading depression indicate potential of the method to evaluate the pathophysiological conditions in brain tissue.

原稿種別: 英語

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