血液透析患者の透析前後における血液の複素比誘電率と生化学成分との相関分析

カテゴリ: 論文誌(論文単位)

グループ名: 【A】基礎・材料・共通部門

発行日: 2012/08/01

タイトル(英語): Correlation Analysis between Complex Relative Permittivity and Biochemical Components for Blood of Dialysis Patients before and after Hemodialysis

著者名: 武田　明（中部大学生命健康科学部臨床工学科／名古屋工業大学大学院），高田　和之（豊田工業高等専門学校），長尾　尋智（岩倉病院），王　建青（名古屋工業大学大学院），藤原　修（名古屋工業大学大学院）

著者名(英語): Akira Takeda (Chubu University/Graduate School of Engineering, Nagoya Institute of Technology), Kazuyuki Takata (Toyota National Colleges of Technology), Hirotomo Nagao (Iwakura Hospital), Jianqing Wang (Graduate School of Engineering, Nagoya Institute of Technology), Osamu Fujiwara (Graduate School of Engineering, Nagoya Institute of Technology)

キーワード: 透析患者，開放終端同軸プローブ，血液，複素比誘電率，血液成分，相関分析　　dialysis patients，open-ended coaxial probe，blood，complex relative permittivity，blood components，correlation analysis

要約(英語): We previously measured for healthy subjects and patients who require hemodialysis the complex relative permittivity (εr´-jεr´´) of whole blood, and found that εr´-axis intercept εrt´ of straight line approximation to the Cole-Cole plots at frequencies from 200 MHz to 1GHz is significantly different with a level of less than 1% among its averaged values for healthy subjects and patients before and after dialysis, though any correlations between εrt´ and blood urea nitrogen (BUN) and creatinine being used as main indices for hemodialysis evaluation have not so far been clarified.In this study, to make correlation analyses between the intercept εrt´ and blood biochemical components for nine patients before and after hemodialysis, we measured six kinds of their blood components including BUN and creatinine, and calculated their Pearson product-moment correlation coefficients for εrt´ along with significant probability P based on a t-test. It should be noted that P is a reference probability to determine whether or not a null hypothesis can be rejected, and that the P value of 0.05 is commonly used as a significance level for statistical test. As a result, we found that a strong correlation with P < 0.05 is observed between εrt´ and albumin, while there are not always significant correlations with P > 0.05 between εrt´ and other blood components including BUN and creatinine. Although albumin is not used as an index for hemodialysis efficiency, it can reflect water amount in blood vessels and liver operation. This finding implies that εrt´ could be used as an index for evaluating blood viscosity and liver function.

本誌: 電気学会論文誌A（基礎・材料・共通部門誌） Vol.132 No.8 （2012）

本誌掲載ページ: 616-622 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejfms/132/8/132_616/_article/-char/ja/