反復経頭蓋磁気刺激の刺激部位及び頻度が事象関連電位に与える影響

カテゴリ: 論文誌(論文単位)

グループ名: 【A】基礎・材料・共通部門

発行日: 2013/08/01

タイトル(英語): Effects of Stimulation Points and Stimulus Frequency to Event-Related Potentials by Repetitive Transcranial Magnetic Stimulation

著者名: 佐藤　綾（純真学園大学保健医療学部），鳥居　徹也（純真学園大学保健医療学部），中原　由木子（純真学園大学保健医療学部），岩橋　正國（東海大学産業工学部），伊藤　裕司（純真学園大学保健医療学部），伊良皆　啓治（九州大学大学院システム情報科学研究院システム生命科学府）

著者名(英語): Aya Sato (Faculty of Health Sciences, Junshin Gakuen University), Tetsuya Torii (Faculty of Health Sciences, Junshin Gakuen University), Yukiko Nakahara (Faculty of Health Sciences, Junshin Gakuen University), Masakuni Iwahashi (Faculty of Industrial Engineering, Tokai University), Yuji Ito (Faculty of Health Sciences, Junshin Gakuen University), Keiji Iramina (Graduate School of Systems Life Sciences, Kyushu University)

キーワード: 反復経頭蓋磁気刺激，縁上回，前頭前野背外側部，P300潜時，刺激頻度　　repetitive transcranial magnetic stimulation (rTMS)，supramarginal gyrus (SMG)，dorsolateral prefrontal cortex (DLPFC)，P300 latency，frequency-dependent

要約(英語): The present study analyzed the effects of repetitive transcranial magnetic stimulation (rTMS) on brain activity. P300 latency of event-related potential (ERP) was used to evaluate the effect of low-frequency and short-term rTMS. We investigated the effect of P300 latency by 1.0 or 0.5 rTMS over the supramarginal gyrus (SMGs) and dorsolateral prefrontal cortex (DLPFCs). The P300 of ERP was elicited by auditory odd-ball task, which was delivered before and shortly after rTMS. ERP was measured prior to rTMS as a control, and after the rTMS. The rTMS was performed for 100 pulses. We found that the individual frequency difference of rTMS affected P300 latencies. Compared to the control, with 1.0 Hz-rTMS to the left-SMG, P300 latencies decreased. Latencies were shorted by approximately 18 ms at Fz electrode. With 0.5 Hz-rTMS to the left-SMG and 1.0 Hz-rTMS to the left-DLPFC, P300 latencies increased. Latencies were lengthened by approximately 26 ms at Fz electrode with 0.5 Hz-rTMS to the left-SMG, and by approximately 18 ms at Fz electrode with 1 Hz-rTMS to the left-DLPFC. In contrast, P300 latency was little altered by rTMS over the right-SMG and right-DLPFC. The results suggested that the effect of low-frequency rTMS had difference by stimulus frequency and stimulation point.

本誌: 電気学会論文誌A（基礎・材料・共通部門誌） Vol.133 No.8 （2013）

本誌掲載ページ: 445-450 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejfms/133/8/133_445/_article/-char/ja/