二次元X線血管造影画像による心筋灌流計測：カテーテルを用いたキャリブレーション法

カテゴリ: 論文誌(論文単位)

グループ名: 【C】電子・情報・システム部門

発行日: 2016/09/01

タイトル(英語): New Catheter-based Calibration Method for 2D X-ray Angiography Myocardial Perfusion

著者名: 坂口　卓弥（東芝メディカルシステムズ／東京工業大学），岩井　春樹（東芝メディカルシステムズ），長江　亮一（東芝メディカルシステムズ），夏目　貴弘（藤田保健衛生大学），市原　隆（藤田保健衛生大学），八木　透（東京工業大学）

著者名(英語): Takuya Sakaguchi (Toshiba Medical Systems Corporation/Tokyo Institute of Technology), Haruki Iwai (Toshiba Medical Systems Corporation), Ryoichi Nagae (Toshiba Medical Systems Corporation), Takahiro Natsume (Fujita Health University), Takashi Ichihara (Fujita Health University), Tohru Yagi (Tokyo Institute of Technology)

キーワード: 灌流計測，画像処理，キャリブレーション，X線血管造影，カテーテル　　Perfusion，Image Processing，Calibration，X-ray Angiography，Catheter

要約(英語): Assessment of myocardial perfusion in 2D X-ray angiography image during coronary interventional treatment is important for better patient outcome. It is necessary for 2D image signal intensity to lineally relate with amount of contrast agent in body for quantitative perfusion analysis. However, it is not linear because of scatter and beam hardening. The aim of this study is to propose simple and practical calibration method for linear relationship. The image signal intensity of the catheter is used to estimate scatter ratio and patient body thickness, and to generate correction function. This correction function is applied to all 2D image pixels to generate corrected image. For verification, 370 mg/ml iodine contrast agent in a 2-mm-diameter silicone tube was used, and correction function was generated. The generated correction function was used to correct image signal intensity of 15 different amount of contrast agent. The corrected image signal intensity were compared with the actual. The mean error between the actual and estimated value was 4.8%. The linear regression line slope was 0.97 and correlation coefficient was R=0.998. The proposed method was confirmed to achieve a good linear relationship between 2D image signal intensity and amount of contrast agent in body.

本誌: 電気学会論文誌C（電子・情報・システム部門誌） Vol.136 No.9 （2016） 特集：神経工学・サイバネティックス・生体工学

本誌掲載ページ: 1305-1311 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejeiss/136/9/136_1305/_article/-char/ja/