ラット聴覚皮質における聴覚タスク中のマイクロ皮質脳波計測

カテゴリ: 論文誌(論文単位)

グループ名: 【C】電子・情報・システム部門

発行日: 2019/05/01

タイトル(英語): Micro-electrocorticogram Measurement in the Auditory Cortex of Rats during Auditory Tasks

著者名: 石津　光太郎（東京大学大学院情報理工学系研究科），白松(磯口)　知世（東京大学先端科学技術センター），小河原　康一（（株）ユニークメディカル），高橋　宏知（東京大学先端科学技術センター）

著者名(英語): Kotaro Ishizu (Graduate School of Information Science and Technology, The University of Tokyo), Tomoyo Isoguchi Shiramatsu (Research Center for Advanced Science and Technology, The University of Tokyo), Koichi Ogawara (Unique Medical CO., LTD.), Hirokazu Takahashi (Research Center for Advanced Science and Technology, The University of Tokyo)

キーワード: 皮質脳波，ラット，慢性計測，聴覚野，覚醒，麻酔　　electrocorticogram，rat，chronical measurement，auditory cortex，arousal，anesthesia

要約(英語): We designed an experimental system to measure micro-electrocorticograms (μECoG) with 4×4 epi-dura electrodes implanted in the temporal cortex in a head-fix preparation of awake rats. During measurement, rats were allowed to pull a lever voluntarily, which was associated with delivery of water reward. With the setup, we trained rats to report conscious perception of tone and mapped the auditory evoked potentials (AEP) around the audible threshold. We demonstrated that conscious perception was associated with P3 wave rather than the middle latency AEP. Thus, our experimental setup was able to characterize μECoG during auditory tasks, opening a new avenue to investigate the neural correlates of consciousness.

本誌: 電気学会論文誌C（電子・情報・システム部門誌） Vol.139 No.5 （2019） 特集Ⅰ：電子・情報・システム技術とものづくり　特集Ⅱ：生体を診る・解く・支える技術

本誌掲載ページ: 625-631 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejeiss/139/5/139_625/_article/-char/ja/