Exploring a Method for Inter-module Time Delay Training in a Semi-separated Dissociated Neuronal Network

カテゴリ: 論文誌(論文単位)

グループ名: 【C】電子・情報・システム部門

発行日: 2019/07/01

タイトル(英語): Exploring a Method for Inter-module Time Delay Training in a Semi-separated Dissociated Neuronal Network

著者名: Chih-Hsiang Chang (Department of Precision Engineering, School of Engineering, The University of Tokyo), Kenta Shimba (Department of Precision Engineering, School of Engineering, The University of Tokyo), Takahiro Asahina (Department of Precision Engineer

著者名(英語): Chih-Hsiang Chang (Department of Precision Engineering, School of Engineering, The University of Tokyo), Kenta Shimba (Department of Precision Engineering, School of Engineering, The University of Tokyo), Takahiro Asahina (Department of Precision Engineering, School of Engineering, The University of Tokyo), Kiyoshi Kotani (Research Center for Advanced Science and Technology, The University of Tokyo), Yasuhiko Jimbo (Department of Precision Engineering, School of Engineering, The University of Tokyo)

キーワード: temporal memory，time-delay stimulation，dissociated neuronal network

要約(英語): Time-delay stimulation in rat cortical slices is considered to be a good experimental model for studying temporal learning, an intrinsic property of the cortical circuit. However, limited knowledge exists surrounding the mechanism of how stimulation with fixed-interval modifies network dynamics. Here, we aimed to elucidate network structure dependency in temporal learning by examining whether the same stimulation is affective for dissociated cultures. A neuronal network with a modular structure was formed with a micro-fabricated device. While training stimulation was effective for altering firing rate, no clear difference was shown in network dynamics, suggesting that the same stimulation used in a slice culture was insufficient for dissociated networks.

本誌: 電気学会論文誌C（電子・情報・システム部門誌） Vol.139 No.7 （2019） 特集：平成30年電子・情報・システム部門大会

本誌掲載ページ: 816-817 p

原稿種別: 研究開発レター／英語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejeiss/139/7/139_816/_article/-char/ja/