マウス褥瘡モデルにおける電界の作用

カテゴリ: 論文誌(論文単位)

グループ名: 【C】電子・情報・システム部門

発行日: 2022/10/01

タイトル(英語): Effects of 50Hz Electric Field on a Mouse Model of a Decubitus Ulcer Produced by Skin Compression

著者名: 原川　信二（帯広畜産大学,生命平衡科学講座（白寿）／白寿生科学研究所），堀　卓也（帯広畜産大学,生命平衡科学講座（白寿）），鈴木　宏志（帯広畜産大学,生命平衡科学講座（白寿））

著者名(英語): Shinji Harakawa (Bio-Self-Regulating Science Laboratory, Obihiro University of Agriculture and Veterinary Medicine/Hakuju Institute for Health Science Co., Ltd.), Takuya Hori (Bio-Self-Regulating Science Laboratory, Obihiro University of Agriculture and Veterinary Medicine), Hiroshi Suzuki (Bio-Self-Regulating Science Laboratory, Obihiro University of Agriculture and Veterinary Medicine)

キーワード: 炎症，創傷治癒，ヘアレスマウス，超低周波，電気刺激，物理療法_x000D_　　inflammatory，wound healing，hairless mouse，extremely low frequency，electrical stimulation，physical therapy

要約(英語): The objective of the present study was to evaluate the effect of extremely low frequency (ELF)-electric field (EF) treatment on decubitus ulcer. Hairless mice (Hr-/kud) were used, and ulcers were formed by magnetic compression of the back skin. The extent of the ulcer was assessed by the diameter of the wound and the crust area. The observation period was 14 days from the day of pressure. Three experimental groups were assigned: a group treated with EF from before the formation of the pressure ulcer until the end of observation, a group that started EF treatment on the day of magnet compression, and a control group that only had pressure ulcer formation. EF was generated at 50Hz at 10kV/m between parallel plate electrodes. EF treatment on the mice was 60 minutes per day. Results showed that the maximum wound diameter was reached in all groups for 3 days. Both decubitus ulcer diameter and crust diameter in the field-treated group were smaller than those in the control group, suggesting an inhibitory effect of ELF-EF on the process of decubitus ulcer development and repair.

本誌: 電気学会論文誌C（電子・情報・システム部門誌） Vol.142 No.10 （2022） 特集：電子材料関連技術の最近の進展

本誌掲載ページ: 1172-1173 p

原稿種別: 研究開発レター／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejeiss/142/10/142_1172/_article/-char/ja/