嗅覚受容体発現細胞を利用した匂いセンサ用自動フロー測定系の開発
嗅覚受容体発現細胞を利用した匂いセンサ用自動フロー測定系の開発
カテゴリ: 論文誌(論文単位)
グループ名: 【E】センサ・マイクロマシン部門
発行日: 2016/07/01
タイトル(英語): Development of Automated Flow Measurement System for Cell-based Odor Sensor
著者名: 祐川 侑司(東京工業大学精密工学研究所),Totok Mujiono(東京工業大学精密工学研究所),中本 高道(東京工業大学精密工学研究所),光野 秀文(東京大学先端科学技術研究センター),中島 裕子(東京大学先端科学技術研究センター),神崎 亮平(東京大学先端科学技術研究センター),三澤 宣雄(豊橋技術科学大学エレクトロニクス先端融合研究所)
著者名(英語): Yuji Sukekawa (Precision and Intelligence Laboratory, Tokyo Institute of Technology), Totok Mujiono (Precision and Intelligence Laboratory, Tokyo Institute of Technology), Takamichi Nakamoto (Precision and Intelligence Laboratory, Tokyo Institute of Technology), Hidefumi Mitsuno (Research Center for Advanced Science and Technology), Yuko Nakajima (Research Center for Advanced Science and Technology), Ryohei Kanzaki (Research Center for Advanced Science and Technology), Nobuo Misawa (Electronics-Inspired Interdisciplinary Research Institute, Toyohashi University of Technology)
キーワード: 嗅覚受容体,自動フロー測定,匂いセンサ,蛍光測定 olfactory receptor,automated flow measurement,odor sensor,fluorescent measurement
要約(英語): Odor sensing system with high sensitivity and selectivity is expected to be realized by using biological mechanisms such as olfactory receptor. We have already developed a cell-based odor sensing system which acquires odorant concentration as a fluorescent intensity change. In the measurement, however, an artifact is likely to happen due to lack of stable and reproducible methods for delivering odorants to biological cells. Therefore, we developed and evaluated the automated flow measurement system which can simultaneously control pump, solenoid valve, and camera. Our system realized automation of solution supply and fluorescent measurement. As a result, our system could reduce artifacts and repeatedly performed measurements with the same sensor cells.
本誌: 電気学会論文誌E(センサ・マイクロマシン部門誌) Vol.136 No.7 (2016) 特集:携帯型ケミカルセンサ・匂いセンサの最前線
本誌掲載ページ: 289-295 p
原稿種別: 論文/日本語
電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejsmas/136/7/136_289/_article/-char/ja/
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