体外診断デバイスに向けた半導体バイオセンシング技術

カテゴリ: 論文誌(論文単位)

グループ名: 【E】センサ・マイクロマシン部門

発行日: 2017/10/01

タイトル(英語): Semiconductor-based Biosensing Technology for in vitro Diagnostic Device

著者名: 坂田　利弥（東京大学大学院工学系研究科）

著者名(英語): Toshiya Sakata (School of Engineering, The University of Tokyo)

キーワード: 半導体，バイオセンシング，体外診断　　semiconductor，biosensing，in vitro diagnosis

要約(英語): In this study, we report a biosensing method to analyze and monitor simply and easily biological phenomena such as DNA recognition events, antigen-antibody reaction and cell functions in vitro by use of a semiconductor device. As the most important point, we focus on a direct detection of ions or ionized molecules with charges, because most biological phenomena are related to ionic behaviors such as sodium or potassium ions through ion channel at cell membrane resulted from cell-cell communications, and biomolecules such as DNA molecules have intrinsic molecular charges. That is, the principle of semiconductor-based biosensing device contributes to directly detect biomolecular charges. Thus, the platform based on a semiconductor-based biosensor is suitable for a label-free and noninvasive biosensing detection device in the field of in vitro diagnosis (IVD).

本誌: 電気学会論文誌E（センサ・マイクロマシン部門誌） Vol.137 No.10 （2017） 特集：バイオマイクロシステムの基礎と応用

本誌掲載ページ: 296-300 p

原稿種別: 解説／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejsmas/137/10/137_296/_article/-char/ja/