非侵襲診断を目指した生化学式ガスセンサと可視化計測システムに関するレビュー

カテゴリ: 論文誌(論文単位)

グループ名: 【E】センサ・マイクロマシン部門

発行日: 2020/11/01

タイトル(英語): Biochemical Gas Sensor and Gas Imaging System for Non-invasive Screening: A Review

著者名: 荒川　貴博（東京医科歯科大学 生体材料工学研究所），飯谷　健太（東京医科歯科大学 生体材料工学研究所），當麻　浩司（東京医科歯科大学 生体材料工学研究所），三林　浩二（東京医科歯科大学 生体材料工学研究所）

著者名(英語): Takahiro Arakawa (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University), Kenta Iitani (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University), Koji Toma (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University), Kohji Mitsubayashi (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University)

キーワード: 生体ガス，非侵襲計測，ガスセンサ，アセトン，エタノール，可視化イメージング　　human volatile chemicals，non-invasive measurement，gas sensor，acetone，ethanol，imaging

要約(英語): The human body emits various volatile molecules, depending on a person's genetics, stress, disease and so on. The volatile organic compounds (VOCs) can be found in human transpiration, breath and transdermal gas emanated from skin. In this review, a biochemical gas sensor “bio-sniffer” and a gas imaging system “sniff-cam” for monitoring of VOCs such as acetone, ethanol and acetaldehyde were presented. Firstly, a high-sensitive acetone biochemical gas sensor was demonstrated and measure exhaled breath acetone concentration, and assess lipid metabolism based on breath acetone analysis. Secondly, a fluorometric imaging system for ethanol vapor released from human breath and palm skin was presented. This imaging system measures ethanol vapor concentrations as intensities of fluorescence through an enzymatic reaction. These biochemical gas sensors and imaging system of VOCs showed a rapidly and accurately responses and measurement, which could lead an analysis to metabolism function and non-invasive screening at real time in the near future.

本誌: 電気学会論文誌E（センサ・マイクロマシン部門誌） Vol.140 No.11 （2020） 特集：Society 5.0を支えるケミカルセンサ

本誌掲載ページ: 321-327 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejsmas/140/11/140_321/_article/-char/ja/