Wireless Stent Flow Sensor System for the Evaluation of Breathing Airflow in the Airway of Experimental Animals

カテゴリ: 論文誌(論文単位)

グループ名: 【E】センサ・マイクロマシン部門

発行日: 2022/01/01

タイトル(英語): Wireless Stent Flow Sensor System for the Evaluation of Breathing Airflow in the Airway of Experimental Animals

著者名: Yoshihiro Hasegawa (Hiroshima City University), Hayato Noma (Hiroshima City University), Miyoko Matsushima (Nagoya University), Shin Hasegawa (COSMOSWEB Co., Ltd.), Tsutomu Kawabe (Nagoya University), Mitsuhiro Shikida (Hiroshima City University)

著者名(英語): Yoshihiro Hasegawa (Hiroshima City University), Hayato Noma (Hiroshima City University), Miyoko Matsushima (Nagoya University), Shin Hasegawa (COSMOSWEB Co., Ltd.), Tsutomu Kawabe (Nagoya University), Mitsuhiro Shikida (Hiroshima City University)

キーワード: flow sensor，stent，breathing，in-situ，animal experiment

要約(英語): A wireless stent flow sensor system was developed to evaluate the changes in breathing characteristics in the airways of experimental animals caused due to drug administration under free movement conditions for drug development. The system was composed of a stent flow sensor, a signal conditioning module, and a PC module. To develop the stent flow sensor, a tube flow sensor and a stent structure were separately fabricated, and they were interlocked at the connection area formed on both elements. The analog sensor outputs were converted into digital outputs with a sampling frequency of 1.0 kHz in a signal conditioning module and transmitted to a PC module through Bluetooth Low Energy 5.0 operated at 2.4 GHz, as the wireless communication. The stent flow sensor and the signal conditioning module were operated using a 165-mAh battery. A simulation experiment was conducted using a plush doll after obtaining calibration curves. A transparent tube was used as the airway and it was placed inside the doll, and an artificial ventilator designed for a small experimental animal was connected to the tube. The stent flow sensor fixed inside the tube was connected to the airway tube, and the signal conditioning module was placed on the back of the neck of the doll. The stent flow sensor output was successfully transmitted to the PC module through Bluetooth. It was demonstrated that the system developed in this study can measure the breathing airflow with a tidal volume accuracy of less than 3.7%.

本誌: 電気学会論文誌E（センサ・マイクロマシン部門誌） Vol.142 No.1 （2022） 特集：センサ・マイクロマシン英文特集号

本誌掲載ページ: 2023/02/07 p

原稿種別: 論文／英語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejsmas/142/1/142_2/_article/-char/ja/