折畳式Finger-Poweredマイクロ流体デバイスを用いた唾液中尿酸センシングシステム

カテゴリ: 論文誌(論文単位)

グループ名: 【E】センサ・マイクロマシン部門

発行日: 2022/03/01

タイトル(英語): Salivary Uric Acid Sensor using The Fordable ‘Finger-Powered' Microfluidic Device

著者名: 工藤　寛之（明治大学理工学部），柴原　卓哉（明治大学理工学部），東條　良紀（明治大学理工学部）

著者名(英語): Hiroyuki Kudo (Meiji University), Takuya Shibahara (Meiji University), Yoshiki Tojyo (Meiji University)

キーワード: バイオセンサ，生体計測，尿酸，電気化学，ヘルスケア　　biosensor，bioinstrumentation，uric Acid，electrochemical，healthcare

要約(英語): Here, we report a novel biosensing system using a finger-powered microfluidic device, which is suitable for daily self-testing of uric acid in saliva. To realize the rapid determination of salivary uric acid, the biosensing system measures directly from the paper-based saliva sampling device. The microfluidic device has the diaphragm pump, the reagent reservoir, and the reaction cell in which the electrochemical uric acid biosensor is embedded. Once the microfluidic chip has been folded, the finger-powered microfluidic device prepares the reagent containing the saliva, which is ready to measure. A wireless potentiostat for electrochemical measurement of uric acid with the biosensor was also developed. Combining these elements together, the whole process from saliva sampling to determination was completed in less than a minute (Sensitivity: 0.03 nA/μM). The measurement results were also consistent with that measured using a commercially available uric acid determination kit. Hence, our method is expected to have the potential to enhance the use of biochemical information in the field of healthcare IoT.

本誌: 電気学会論文誌E（センサ・マイクロマシン部門誌） Vol.142 No.3 （2022） 特集：新時代バイオナノマイクロシステム

本誌掲載ページ: 38-42 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejsmas/142/3/142_38/_article/-char/ja/