血液VOCsの非侵襲バイオ蛍光計測及びイメージング解析に基づく新規ウエアラブルセンサの開発

カテゴリ: 論文誌(論文単位)

グループ名: 【E】センサ・マイクロマシン部門

発行日: 2024/11/01

タイトル(英語): Non-invasive Biofluorometirc Sensing and Imaging Analysis of Blood VOCs for Novel Wearable Sensor

著者名: 三林　浩二（東京科学大学 生体材料工学研究所）

著者名(英語): Kohji Mitsubayashi (Laboratory for Biomaterials and Bioengineering, Institute of Science Tokyo)

キーワード: 非侵襲計測，気相バイオセンサ，バイオ蛍光計測，ガスイメージング，ウエアラブル・バイオセンシング　　non-invasive measurement，gas-phase biosensor，biofluorometry，gas imaging，wearable biosensing

要約(英語): Blood contains volatile biomarkers related to diseases and metabolism. We developed a biofluorometric gas sensor that measures acetone with high sensitivity and confirmed its significance in lipid metabolism and diabetes when applied to breath measurement. Furthermore, regarding transcutaneous gases that permeate through the skin from blood, a biofluorometric gas-imaging system for ethanol vapor as the target chemical was developed and analyzed the secretion dynamics of transcutaneous gases at each skin site, thus showing the stable release of blood-derived volatile markers from the ear canal. Based on the results, we have developed a headphone-type gas sensor and succeeded in continuous and stable transcutaneous gas measurement, thus indicating the future potential of a novel wearable biosensor for blood VOCs.

本誌: 電気学会論文誌E（センサ・マイクロマシン部門誌） Vol.144 No.11 （2024） 特集：化学物質の高次センシングと解析技術

本誌掲載ページ: 339-344 p

原稿種別: 解説／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejsmas/144/11/144_339/_article/-char/ja/