ラットの聴皮質と視床における3次元多点同時計測システムの開発

カテゴリ: 論文誌(論文単位)

グループ名: 【C】電子・情報・システム部門

発行日: 2014/08/01

タイトル(英語): Simultaneous 3-dimensional Multi-point Recording System from Auditory Cortex and Thalamus in Rat

著者名: 高橋　和佐（東京大学大学院情報理工学系研究科），白松（磯口）　知世（東京大学先端科学技術センター），野田　貴大（東京大学先端科学技術センター），神崎　亮平（東京大学大学院情報理工学系研究科／東京大学先端科学技術センター），中原　はるか（帝京大学医学部），高橋　宏知（東京大学大学院情報理工学系研究科／東京大学先端科学技術センター／科学技術振興機構さきがけ）

著者名(英語): Kazusa Takahashi (Graduate School of Information Science and Technology, The University of Tokyo), Tomoyo Shiramatsu (Isoguchi) (Research Center for Advanced Science and Technology, The University of Tokyo), Takahiro Noda (Research Center for Advanced Science and Technology, The University of Tokyo), Ryohei Kanzaki (Graduate School of Information Science and Technology, The University of Tokyo/Research Center for Advanced Science and Technology, The University of Tokyo), Haruka Nakahara (School of Medicine, Teikyo University), Hirokazu Takahashi (Graduate School of Information Science and Technology, The University of Tokyo/Research Center for Advanced Science and Technology, The University of Tokyo/JST PRESTO)

キーワード: 聴皮質，視床，ラット，微小電極アレイ　　auditory cortex，thalamus，rat，microelectrode array

要約(英語): We developed an experimental system to simultaneously characterize tonotopic activities of both the auditory cortex and thalamus of rats, each with a number of microelectrodes. The system consisted of a custom-designed surface electrode array and depth electrode array. The surface electrode array had 64 recording points in a 4.5 mm × 3 mm area. Between the recording points holes were made, through which the depth array was inserted. The depth array had 3 shanks, each of which was 6 mm long with an inter-shank distance of 500 µm. Each shank had 15 recording sites for the thalamus and 17 for the auditory cortex. To precisely insert the depth array perpendicularly to the cortical surface, a laser displacement meter was used. We measured tone-evoked local field potentials and multi-unit activities in the auditory cortex and thalamus of rats under anesthesia, and characterized tonotopic maps simultaneously in the auditory cortex and thalamus.

本誌: 電気学会論文誌C（電子・情報・システム部門誌） Vol.134 No.8 （2014） 特集：産業界における新たな通信・ネットワーク技術の活用

本誌掲載ページ: 1064-1070 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejeiss/134/8/134_1064/_article/-char/ja/