キャリブレーションを必要としない光学的手法による非侵襲・連続的ヘマトクリット計測

カテゴリ: 論文誌(論文単位)

グループ名: 【C】電子・情報・システム部門

発行日: 2015/04/01

タイトル(英語): Non-invasive and Continuous Hematocrit Measurement by Optical Method without Calibration

著者名: 江國　翔太（筑波大学 グローバル教育院），山海　嘉之（筑波大学 システム情報系）

著者名(英語): Shota Ekuni (School of Integrative and Global Majors, University of Tsukuba), Yoshiyuki Sankai (Faculty of Engineering, Information and Systems, University of Tsukuba)

キーワード: 体外循環装置，血栓性疾患，ヘマトクリット，近赤外光計測　　extracorporeal circulation apparatus，thrombosis，hematocrit，near-infrared spectroscopy

要約(英語): Hematocrit monitoring in an extracorporeal circulation apparatus is required for detection of adverse events such as hypotension and bleeding. Nevertheless we have researched non-invasive and continuous hematocrit measurements using optical methods, it remains a challenge to measure absolute levels of hematocrit without calibration. The purpose of this study is to develop an optical hematocrit measurement method without calibration, and to confirm the effectiveness in in-vitro blood experiments. We have developed an improvement method for dual wavelength and detector model by maximizing the difference of optical path lengths. Based on the proposed method, a measurement system has been developed. In the basic blood experiment, the correlation of hematocrit and calculated values by the proposed method has been confirmed. Then, we have conducted hematocrit measurement experiments with attachment errors and change of blood flow. The data indicate that the accuracy of the proposed method without calibration has been equivalent to that of an invasive method, which is employed in clinical practice. In conclusion, we have confirmed that the proposed method is effective for non-invasive and continuous hematocrit measurements.

本誌: 電気学会論文誌C（電子・情報・システム部門誌） Vol.135 No.4 （2015） 特集：知覚情報技術の最前線

本誌掲載ページ: 387-395 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejeiss/135/4/135_387/_article/-char/ja/