両面成形型自律遠心マイクロ分注機構の開発と動作安定性の評価

カテゴリ: 論文誌(論文単位)

グループ名: 【C】電子・情報・システム部門

発行日: 2020/04/01

タイトル(英語): Development of a Double Side Patterning Autonomous Centrifugal Microfluidic Dispenser and Evaluation of Stability

著者名: 岡本　俊哉（山梨大学大学院医工農学総合教育部工学専攻／日本学術振興会），浮田　芳昭（山梨大学大学院総合研究部工学域）

著者名(英語): Shunya Okamoto (Department of Engineering, Integrated Graduate School of Medicine, Engineering, and Agricultural Sciences, Graduate School of University of Yamanashi/Japan Society for the Promotion of Science), Yoshiaki Ukita (Faculty of Engineering, Graduate Faculty of Interdisciplinary Research, Graduate School of University of Yamanashi)

キーワード: 遠心マイクロ流体デバイス，両面成形，分注，自律制御，集積化，臨床現場即時診断　　centrifugal microfluidic device，double side pattering，dispenser，autonomous，integration，point of care testing (POCT)

要約(英語): This paper reports on the fabrication and demonstration of a novel autonomous centrifugal microfluidic dispenser that microchannels are patterned on the double side of the microchip. The dispenser executes metering of dispensing volume and injection into each target chamber. In a capillary dispenser that was previously reported is unstable, because liquids in the chambers during metering are kept by capillary force. However, the present double side patterning dispenser does not rely on capillary forces, owing to siphon valves, which three-dimensionally cross chambers and microchannels. In the experiments, it was confirmed that the double side patterning dispenser has a high accuracy of dispensing volume. Moreover, higher stability in repeatedly dispensing test was confirmed, in comparison with the capillary dispenser the. Therefore, it is expected to realize high stability and compact analytical systems, which are suitable for POCT, by integrating the dispenser on analytical devices.

本誌: 電気学会論文誌C（電子・情報・システム部門誌） Vol.140 No.4 （2020） 特集：ナノ構造の医療・バイオ応用技術

本誌掲載ページ: 457-464 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejeiss/140/4/140_457/_article/-char/ja/