射出成形を用いた接合型中空マイクロニードルアレイの作製及び穿刺特性評価

カテゴリ: 論文誌(論文単位)

グループ名: 【E】センサ・マイクロマシン部門

発行日: 2012/05/01

タイトル(英語): Fabrication of Bonding-Type Hollow Microneedle Array by Injection Molding and Evaluation of its Puncture Characteristics

著者名: 小粥　教幸（光産業創成大学院大学　光産業創成研究科／ASTI（株） AMD推進室），杉村　竜（ASTI（株） AMD推進室），田丸　卓也（ASTI（株） AMD推進室），瀧口　義浩（光産業創成大学院大学　光産業創成研究科）

著者名(英語): Noriyuki Ogai (The Graduate School for the Creation of New Photonics Industries/ASTI CORPORATION AMD (Advanced Micromachining Devices)), Ryo Sugimura (ASTI CORPORATION AMD (Advanced Micromachining Devices)), Takuya Tamaru (ASTI CORPORATION AMD (Advanced Micromachining Devices)), Yoshihiro Takiguchi (The Graduate School for the Creation of New Photonics Industries)

キーワード: 接合型中空マイクロニードルアレイ，ポリ乳酸，射出成形，穿刺力，穿刺深さ　　Bonding-type hollow microneedle array，Polylactic acid (PLA)，Injection molding，Puncture force，Puncture depth

要約(英語): A microneedle array which consists from small needles compared to a conventional metal injection needle is expected as a low invasive transdermal medical treatment device, and many fabrication approach have been conducted. In this study, we fabricated plastic hollow microneedle array by a fabrication method based on the combination of injection molding, bonding and assembly techniques. To evaluate puncture characteristics of the fabricated needle, we measured a puncture force to silicone rubber by experimental equipment using loadcell and automatic stage. Furthermore, we propose and demonstrate a new method to measure actual punctured depth from punctured trace on the needle surface modified by O2 plasma treatment.

本誌: 電気学会論文誌E（センサ・マイクロマシン部門誌） Vol.132 No.5 （2012）

本誌掲載ページ: 133-138 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejsmas/132/5/132_5_133/_article/-char/ja/