POCTを指向した自律型遠心マイクロ分注機構の開発

カテゴリ: 論文誌(論文単位)

グループ名: 【E】センサ・マイクロマシン部門

発行日: 2018/08/01

タイトル(英語): Development of an Autonomous Centrifugal Microfluidic Dispenser for POCT

著者名: 岡本　俊哉（山梨大学大学院医工農学総合教育部工学専攻），浮田　芳昭（山梨大学工学部機械工学科）

著者名(英語): Shunya Okamoto (Department of Eengineering, Integrated Graduate School of Medicine, Engineering, and Agricultural Sciences, Graduate School of University of Yamanashi), Yoshiaki Ukita (Faculty of Engineering, Graduate Faculty of Interdisciplinary Research

キーワード: 遠心マイクロ流体デバイス，分注，自律制御，複数同時分析，臨床現場即時診断，酵素免疫測定法_x000D_　　centrifugal microfluidic device，dispenser，autonomous，multi assay，point of care testing (POCT)，enzyme-linked immune solvent assay (ELISA)

要約(英語): This paper reports on the demonstration of a novel autonomous dispensing system for point of care testing (POCT). Although existing dispensing systems generally employ external triggers, such as changing rotational speed or heating of a device, our dispenser is driven at steady rotational speed without external triggers by using siphons, water-clock based autonomous timing and metering, and capillary forces. It becomes possible to dispense reagents simultaneously into multiple reaction chambers, by using this dispensing system. Simplicity of reagent handlings and uniformity of reaction conditions can be improved. Therefore it is expected to realize highly reliable and low-cost analytical systems, which are suitable for POCT, by integrating the dispenser on analytical devices.

本誌: 電気学会論文誌E（センサ・マイクロマシン部門誌） Vol.138 No.8 （2018） 特集：バーチャルリアリティを実現するセンサ，アクチュエータとディスプレイ

本誌掲載ページ: 370-375 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejsmas/138/8/138_370/_article/-char/ja/