電気化学的測定法によるカーボンナノチューブを用いた免疫センサ電極の評価

カテゴリ: 論文誌(論文単位)

グループ名: 【A】基礎・材料・共通部門

発行日: 2019/09/01

タイトル(英語): Evaluation of Immunoelectrode based on Carbon Nanotube using Electrochemical Measurement Methods

著者名: Tink　Basu（Amitty Institute of Nanotechnology, Amitty University），小野田　光宜（兵庫県立大学 姫路工学キャンパス）

著者名(英語): Tink Basu (Amitty Institute of Nanotechnology, Amitty University), Mitsuyoshi Onoda (Himeji Engineering Campus, University of Hyogo)

キーワード: 免疫センサ，カーボンナノチューブ，キトサン，電気化学インピーダンス分光法，表面吸着制御拡散過程，不均一電子移動反応　　immunosensor，carbon nanotube，chitosan，electrochemical impedance spectroscopy，surface adsorption-controlled diffusion process，heterogeneous electron-transfer process

要約(英語): Much progress in the field of organic nanotechnology and biomolecular electronics for environmental preservation will be expected in 21st century. A bio-device using information transfer-conversion system of the creature is a biosensor. By quick sensing the invasion of the pathogen from the outside, possessing a role which transmits the information to a cell is an immunosensor. The estimation of low density lipoprotein (LDL) cholesterol is important parameters for clinical diagnostics. We have fabricated an immunosensor based on apolipoprotein B (AAB) functionalized carbon nanotubes (CNT) for LDL detection using electrochemical measurement methods. Our proposed immunosensor is on the basis of antibody (AAB)-antigen (LDL) interaction. This immunosensor is found to be selective for LDL and exhibits a wide detection range of LDL shows higher sensitivity and first response. Higher stability of this proposed immunosensor has been observed due to covalent functionalization of AAB on functionalized CNT nanocomposite surface. The most familiar area biotechnology which is based on amicable use of unique biological function towards betterment of human life and environmental conservation cannot deny the important role played by the ions. "Solion" is an electronic circuit device using migration of ions in electrolytic solution.

本誌: 電気学会論文誌A（基礎・材料・共通部門誌） Vol.139 No.9 （2019） 特集：電気電子絶縁材料システムシンポジウム

本誌掲載ページ: 360-366 p

原稿種別: 論文／日本語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejfms/139/9/139_360/_article/-char/ja/