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Edge-enhanced Soft X-ray Phase-contrast Microscopy Exploiting the Near K-edge Optical Properties of Carbon

Edge-enhanced Soft X-ray Phase-contrast Microscopy Exploiting the Near K-edge Optical Properties of Carbon

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カテゴリ: 論文誌(論文単位)

グループ名: 【C】電子・情報・システム部門

発行日: 2014/04/01

タイトル(英語): Edge-enhanced Soft X-ray Phase-contrast Microscopy Exploiting the Near K-edge Optical Properties of Carbon

著者名: Andrew Domondon (Faculty of Science and Engineering, Waseda University), Nandor Bokor (Dept. of Physics, Budapest University of Technology and Economics), Yoshinori Iketaki (Future Creation Laboratory, Olympus Co., Ltd.)

著者名(英語): Andrew Domondon (Faculty of Science and Engineering, Waseda University), Nandor Bokor (Dept. of Physics, Budapest University of Technology and Economics), Yoshinori Iketaki (Future Creation Laboratory, Olympus Co., Ltd.)

キーワード: X-ray microscopy,edge-enhancement,tryptophan,π* anti-bonding orbital,Kramers-Kronig relation

要約(英語): This paper proposes a method of microscopy we call “edge-enhanced soft X-ray phase-contrast microscopy”. It employs a Hilbert-transform microscope setup and exploits the fact that for the same soft X-ray wavelength there is a marked difference in the refractive index for water and carbon. This method produces an edge-enhancement phase contrast image of the molecules that results from the difference in how the X-rays interact with water and the organic molecule of interest. Since this method can detect very small phase jumps, it enables one to observe molecules in vivo with high spatial resolution and high contrast. The results of simulating the technique using the absorption spectrum of tryptophan are presented and suggest that the proposed method will be useful for obtaining images of biological molecules in vivo.

本誌: 電気学会論文誌C(電子・情報・システム部門誌) Vol.134 No.4 (2014) 特集:量子ビームによるナノバイオ物理応用技術

本誌掲載ページ: 521-523 p

原稿種別: 資料/英語

電子版へのリンク: https://www.jstage.jst.go.jp/article/ieejeiss/134/4/134_521/_article/-char/ja/

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